strontium citrate pros and cons

1992;19(3):197-201. View abstract. 2010;21(12):1993-2002. Expert.Opin.Investig.Drugs 2004;13(7):857-864. Because strontium atoms are heavier than calcium atoms, swapping some of the calcium atoms with strontium atoms will make the bone mineral density appear to increase. 2008;67(3):335-339. All rights reserved. Delayed strontium absorption in post-menopausal osteoporosis and osteomalacia. Scientists havent tested these supplements much, so theres not enough research to know if they fight osteoporosis. [2] Royal Osteoporosis Society. View abstract. El-Hajj Fuleihan G. Strontium ranelate--a novel therapy for osteoporosis or a permutation of the same? Diagnosis and Management. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Osteoporos.Int. Robinson RG, Preston DF, Schiefelbein M, Baxter KG. Arch.Intern.Med. Expert.Opin.Pharmacother. It's not known if strontium contained in dietary supplements has these effects. 2008;67(12):1736-1738. View abstract. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. Hahn, G. S. Strontium is a potent and selective inhibitor of sensory irritation. View abstract. The American Bone Health Fracture Risk Calculator estimates fracture risk for women and men over age 45. strontium is unlikely to have a net beneficial effect in osteoporosis and its use is declining as a consequence. View abstract. Zhai, H., Hannon, W., Hahn, G. S., Harper, R. A., Pelosi, A., and Maibach, H. I. Strontium nitrate decreased histamine-induced itch magnitude and duration in man. Perit Dial Int 1998;18:410-4. Does anyone take Forteo ? Posted: 09/28/19;Revised: 09/25/20. Cochrane Database Syst Rev 2005;(2):CD002946. @faith123, recently posted about having a second reclast infusion recently here, https://connect.mayoclinic.org/discussion/reclast-infusion/. Incidence and mortality of venous thrombosis: a population-based study. Effect of osteoporosis treatments on risk of non-vertebral fractures: review and meta-analysis of intention-to-treat studies. Maheu E, Mazieres B, Valat JP, et al. Roux, C., Reginster, J. Y., Fechtenbaum, J., Kolta, S., Sawicki, A., Tulassay, Z., Luisetto, G., Padrino, J. M., Doyle, D., Prince, R., Fardellone, P., Sorensen, O. H., and Meunier, P. J. Vertebral fracture risk reduction with strontium ranelate in women with postmenopausal osteoporosis is independent of baseline risk factors. Strontium Ranelate returns to the UK as an osteoporosis drug treatment. 2019https://theros.org.uk/latest-news/2019-01-14-strontium-ranelate-returns-to-the-uk-as-an-osteoporosis-drug-treatment. Meanwhile, strontium citrate features a 31% elemental strontium and only 69% citrate. Osteoporos.Int. Available at: https://www.fda.gov/cder/ogd/approvals/1stgen0103.htm. American Bone Health4208 Six Forks RoadSuite 1000Raleigh, NC 27609. Estrogens might decrease how fast the body gets rid of strontium. 5 Possible (and Controversial) Health Benefits, The Foods, Supplements & Oils to Increase Bone Healing, Daniel Fast: Benefits for Your Spiritual, Emotional and Physical Health, 15 Fermented Foods for a Healthy Gut and Overall Health, 9 Proven Black Seed Oil Benefits that Boost Your Health, L-Glutamine Benefits Leaky Gut & Metabolism, Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More. View abstract. Seafood is a top source of Sr, but it can also be found in smaller quantities in whole milk, grains,beans, spinach, lettuce, celery, androot vegetableslike carrots and potatoes. Roque, I. Figuls, Martinez-Zapata, M. J., Scott-Brown, M., and Alonso-Coello, P. Radioisotopes for metastatic bone pain. N.Engl.J.Med. Prostate cancer. Lets take a look at the possible health benefits of strontium. Strontium is a mineral found in seawater and soil. 1980;51(10):578-581. Dr. Lanis No-Nonsense Bone Health Guide. View abstract. Afflitto, J., Schmid, R., Esposito, A., Toddywala, R., and Gaffar, A. Fluoride availability in human saliva after dentifrice use: correlation with anticaries effects in rats. View abstract. Kidney Int. Glucosamine therapy for treating osteoarthritis. View abstract. Some people say this supplement improves bone health, but its important to think about its benefits and risks before you decide to take it. Bone 2009;45(2):200-206. A double blind, prospective, placebo-controlled study. Strontium Citrate is one of the most common types of Strontium used in the dietary supplement field for bone health. The body needs zinc for the immune system to work properly. 1996;41(6):543-549. Rheumatol.Int. Note that the numbers in parentheses (1, 2, etc.) Loutit, J. F. Diurnal variation in urinary excretion of calcium and strontium. 2007;357:nihpa40967. Kanapka, J. View abstract. A., Hoiseth, A., Felsenberg, D., Huss, H., Gilbride, J., Schimmer, R. C., and Delmas, P. D. Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. Aging Clin.Exp.Res. Bone mass and markers of bone and calcium metabolism in postmenopausal women treated with 1,25-dihydroxyvitamin D (Calcitrol) for four years. Br.J.Clin.Pharmacol. Strontium ranelate is comprised of 27.8% strontium and 72.2% ranelic acid. Sairanen S, Karkkainen M, Tahtela R, et al. Cochrane Musculoskeletal Group. Bone 2001;28:446-53. (16), Strontiums name comes from Strontian, a village in Scotland. Leeb BF, Schweitzer H, Montag K, Smolen JS. One scientific review published in 2014 by a doctor with admitted ties to pharmaceutical makers concludes, The increased risk for cardiac events with strontium ranelate has been detected in randomized clinical trials but not in real-life observational studies. (9), Ultimately, the European Union now only endorses the use of strontium ranelate in severe cases of osteoporosis with high fracture risk. 1992;19(10):737-740. 1992;63(1):7-12. Brandi ML. Currently, we do not have a way to measure the false increase in bone density that results when you take a supplement or a medication that includes strontium.. Radiat.Environ.Biophys. View abstract. Its been interesting what research has shown to date aboutits use for osteoporosis. Since strontium is denser than calcium, it is difficult to assess actual bone improvement in a DXA scan. View abstract. A prescription form of strontiumstrontium ranelate (the ranelate salt), known as Protelos/Osseor was authorized in the European Union to treat severe osteoporosis in women who have been through the menopause and men who are at high risk of broken bones or fracture in the spine and the hip. Results of a 2-year study. This is more important for postmenopausal women. 1984;55(12):720-725. Concentrations of trace elements in osteoarthritic knee-joint effusions. View abstract. FreshSplash/Getty Images. A prospective, multicenter, three-month, randomized, double-blind, placebo-controlled trial. All rights reserved. Male hormones (Androgens) might decrease how fast the body gets rid of strontium. Krachler, M., Domej, W., and Irgolic, K. J. ***Director's Note:*** These forms are different from the ranelate compound and there have been no studies showing that they are safe or effective. 2013 Sep 4;93(5):520-6. doi: 10.2340/00015555-1564. I did find some information on the Mayo Clinic website on osteoporosis. Arthritis Rheum. 1998;4(2):114-119. If you want to take a strontium supplement, ask your doctor first. That means it may affect how strong your bones are. Strontium results in an overestimation (up to 50%) of the increase in bone density using DXA methods.[3]. Clin.Prev.Dent. JAMA 1995;274:420-4. Accordingto the United States Department of Agriculture, Americans consume around 0.7 pounds celestite, which is used in strontium metal alloys. Liu, J. M., Wai-Chee, Kung A., Pheng, C. S., Zhu, H. M., Zhang, Z. L., Wu, Y. Y., Xu, L., Meng, X. W., Huang, M. L., Chung, L. P., Hussain, N. H., Sufian, S. S., and Chen, J. L. Efficacy and safety of 2 g/day of strontium ranelate in Asian women with postmenopausal osteoporosis. Faith123 may be able to answer a question or two of yours about the reclast infusion treatment and her experience with it. Strontium(89) chloride versus palliative local field radiotherapy in patients with hormonal escaped prostate cancer: a phase III study of the European Organisation for Research and Treatment of Cancer, Genitourinary Group. Although many people have never heard of it before, its a very interesting and somewhat controversial supplement. A., Cosman, F., Lakatos, P., Leung, P. C., Man, Z., Mautalen, C., Mesenbrink, P., Hu, H., Caminis, J., Tong, K., Rosario-Jansen, T., Krasnow, J., Hue, T. F., Sellmeyer, D., Eriksen, E. F., and Cummings, S. R. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. 99% of the strontium found in the human body is in the bone. McAlindon TE, LaValley MP, Gulin JP, Felson DT. Do not take it within 2 hours of ingesting calcium so I take it at bedtime. Sr-89 has been used as a form of treatment to manage pain resulting from bone pain due to cancer. Interested in more discussions like this? Our team includes licensed nutritionists and dietitians, certified health education specialists, as well as certified strength and conditioning specialists, personal trainers and corrective exercise specialists. 1990;34(3):545-560. Zinc is crucial for various functions in the body, including: 1. Overall, the review concludes: For patients with castration-resistant prostate cancer suffering from malignant bone pain, treatment with a bone-seeking radiopharmaceutical is a relevant therapeutic option often resulting in significant pain reduction. 2004;86-A(3):538-545. "Hello @bonelady. For two years, 174 of the men received 2 grams of strontium ranelate per day while 87 men received a placebo. Further research is still needed and it can be dangerous to use these supplements if you have certain health conditions. Keep in mind that more research is still needed to confirm its benefits and safety for some of these uses. View abstract. Get answers to some of the most common questions about osteoporosis treatment. 2002;13(12):925-931. View abstract. Rintelen, B., Neumann, K., and Leeb, B. F. A meta-analysis of controlled clinical studies with diacerein in the treatment of osteoarthritis. 2013 Feb;98(2):592-601. doi: 10.1210/jc.2012-3048. Radiother Oncol 1994;31:33-40. View abstract. You do not know the effectiveness of the supplements. Even though its not considered a nutrient, its known that the human body can absorb strontium and utilize it as it would calcium. I. Inhibition of intestinal calcium absorption and 1,25-dihydroxycholecalciferol synthesis. 2000;11(1):83-91. Eur Urol 2003;44:519-26. Natural strontium has a silvery white metallic color with a tint of yellow. J.Bone Joint Surg.Am. 1977;95(5):982-985. Esomeprazole (Nexium) is not the same medication as esomeprazole strontium, although both are used to treat similar stomach conditions. Strontium may also influence other essential functions, including calcium absorption, bone formation & breakdown, and it restores alkaline pH to improve the health of skin, hair, and nails). . Nonvertebral fracture benefit from oral ibandronate administered daily or with a unique drug-free interval: Results from a pivotal phase III study in postmenopausal osteoporosis (PMO). New treatment strategies: ipriflavone, strontium, vitamin D metabolites and analogs. Osteoporos Int. Reginster, J. Y. and Meunier, P. J. Strontium ranelate phase 2 dose-ranging studies: PREVOS and STRATOS studies. Ann.Rheum.Dis. Effects of oral supplementation with stable strontium. It does not recommend it as a treatment for anyonewho has or has had heart or circulatory problems such as stroke, heart attack, or obstruction of the blood flow in the arteries. View abstract. View abstract. Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others. 11 possible benefits. Next year will be my third year off the reclast so it will be interesting to see what docs will then suggest. Arthritis Rheum 2007;56(7):2267-2277. Harris, S. T., Watts, N. B., Genant, H. K., McKeever, C. D., Hangartner, T., Keller, M., Chesnut, C. H., III, Brown, J., Eriksen, E. F., Hoseyni, M. S., Axelrod, D. W., and Miller, P. D. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. About 99% of the strontium in the human body is concentrated in the bones. JAMA 2000;283:1469-75. (4a) In addition, strontianite is a mineral that comes from concentrations of strontium compounds, and there are several strontium compounds. Springer, 2019. They won't do any studies but the END OF FRACTURES SAYS IT ALL! View abstract. View abstract. View abstract. View abstract. Effectiveness of desensitizing agents. The forms of strontium available over-the-counter in the U.S. or on the Internet are usually strontium citrate or strontium chloride. View abstract. Before you consider calcium supplements, be sure you understand how much calcium you need, the pros and cons of calcium supplements, and which type of supplement to choose. Given that strontium test results are tied to the strontium ion, citrate is your best option to reap its bone-building benefits. The radioactive form of Sr is not available as a dietary supplement, but it is considered to likely be safe when administered by a health care professional by IV. Research shows that a special prescription form of strontium (strontium-89 chloride) given intravenously (by IV) reduces pain from metastatic, Weak and brittle bones (osteoporosis). Ashayeri E, Omogbehin A, Sridhar R, Shankar RA. Cochrane.Database.Syst.Rev. Arthritis Rheum. European Medicines Agency, 2005. Recent important clinical trials of drugs in osteoporosis. View abstract. O'Donnell S, Cranney A, Wells GA, et al. If you are concerned about the bone-thinning disease osteoporosis, you may have heard about treatment with strontium. Note that the numbers in parentheses (1, 2, etc.) View abstract. It also appears that people with strontium in their local water supply seem to have decreased cavity risk. Most calcium supplements are big and difficult to swallow. Dose-dependent effects of strontium on osteoblast function and mineralization. Fidelix, T. S., Soares, B. G., and Trevisani, V. F. Diacerein for osteoarthritis. Doggrell, S. A. View abstract. Spets-Happonen, S., Seppa, L., Korhonen, A., and Alakuijala, P. Accumulation of strontium and fluoride in approximal dental plaque and changes in plaque microflora after rinsing with chlorhexidine-fluoride-strontium solution. Because strontium ranelate is a weak anti-resorptive agent and there are more effective osteoporosis agents in the United States and most countries, we do not use strontium ranelate in postmenopausal women with osteoporosis. View abstract. N.Engl.J.Med. Molybdenum, nickel, cobalt, vanadium, and strontium in total diets. View abstract. In 2013, the committee of the European Medicines Agency (similar to the FDA in the United States) recommended suspending strontium ranelate (brand name Protelos/Osseor) for treating osteoporosis. Strontium is similar to calcium. Les Laboratoires Servier ceased the distribution of Protelos/Osseor in August 2017. However, I dont advocate using these supplements without first reviewing the precautions listed below and talking with your health care provider. What else is it good for? https://americanbonehealth.org/bonesense/why-strontium-is-not-good-for-bone-health/

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